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However, like any medication, GLP-1s come with possible side effects, including: Nausea Vomiting Constipation Pancreatitis Diarrhea Injection site reaction Hair loss Headache Muscle loss Fatigue Anhedonia (lack of joy in eating and other life activities) For a comprehensive list of efficacy and safety data, review the prescribing information for each medication or visit the FDA Adverse Event Reporting System website

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Clinical reality: People usually stop antidepressants because a side effect interferes with sleep, work, intimacy, parenting, or exercise

All calculations were performed using curated and standardized libraries from DB, FDB, Biosynth, Molport and Enamine