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The people who could benefit most from these medications are often those least able to afford them, perpetuating a cycle in which geography, income, and health outcomes remain tightly intertwined

This triple-agonist mechanism creates a three-pronged approach to weight loss: reduced food intake, improved metabolic efficiency, and increased calorie burning

While semaglutide GLP-1 is highly effective, it is important to address potential gastrointestinal side effects, such as nausea and diarrhea, which are generally transient and manageable

No head-to-head RCT data exist, but we recently published a case report describing differences in efficacy of liraglutide compared with semaglutide (once-weekly subcutaneous administration) in an individual with primary BAD (16)