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Clinical research showed skin radiance improvements of 20% on the forehead, reduced wrinkle depth, and visible changes starting at week four of daily use

The efficacy of two drugs, i.e., pilocarpine and bethanechol, that increase production of saliva was tested upon saliva secretion in cancer patients with hypo-salivation following radiation therapy (Gorsky et al., A pilot investigation was conducted to assess the role of serotonergic blockade by using ondansetron, an antagonist of serotonin type-3 receptor (Edelman et al., 1 A receptor and the use of its specific agonist, 8-OH-DPAT, inhibited taste-evoked Ca 2+ release in TRCs and also curtailed ATP release

Del Prato S, Kahn SE, Pavo I, Weerakkody GJ, Yang Z, Doupis J, et al