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To evaluate the functional relevance of the GLP-1R cholesterol binding sites identified during the cgMD simulations, 12 residues were selected within or at the periphery of these sites and mutated to alanine by site-directed mutagenesis (Figure 2F)

Antinuclear Antibodies (ANA) Pattern Analyzes how antibodies bind to cell nuclei, helping identify specific types of autoimmune conditions

Slowed gastric emptying and disrupted digestive enzyme activity can contribute to subclinical malabsorption