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Footprints of oxidative damage (downstream proxies) For downstream damage footprints, prioritize chemically specific assays: lipid peroxidation is best tracked by F 2 -isoprostanes and by MDA/HNE adductsnote that thiobarbituric acidbased colorimetry is prone to artifacts, so LC-MS/MS is preferred over simple spectrophotometric methods (Krl and Brzenicki 2023)

After swallowing the tablet whole (not split, crushed, or chewed), patients must wait at least 30 minutes before eating, drinking anything other than water, or taking other oral medications

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