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One unexpected serious adverse reaction occurred in a NAC-treated patient caused by an erroneous iv infusion rate (1.5g-loading dose-15 min followed by 7.5 g delivered over 3h15min instead of 4 h), causing chest tightness, despite stable vital signs, which was resolved by corticosteroids and discontinuation of iv NAC

Consequently, individuals do not exhibit warning signs of overdose, such as vomiting or loss of consciousness, allowing blood alcohol concentration (BAC) to reach lethal levels unnoticed

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