Recently, two mechanisms involved in the gut-brain axis have attracted increasing attention due to their role in the pathogenesis and progression of PD, namely, disruption of the composition of microorganisms living in the intestine (intestinal microbiome) and dysfunction of enteroendocrine cells, accompanied by impaired signaling through the GLP-1R [60]
1 The 2023 International Evidence-Based Guideline for the Assessment and Management of PCOS, developed by Monash University in partnership with ESHRE, ASRM, the Endocrine Society, and the European Society of Endocrinology, 11 made several practice-defining points
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