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25 A larger, double-blind RCT of 243 cancer patients receiving cisplatin or oxaliplatin and diagnosed with CIPN showed no significant difference in peripheral neuropathic symptoms between oral ALA 600 mg/day orally and placebo but further studies are needed to conclusively determine if ALA could benefit this subset of patients

Side Effects and Complications NAD+ Infusion Symptoms Nausea, abdominal discomfort or cramping, chest pressure or tightness, flushing, dizziness, headache, chills, shaking, vomiting, and fatigue have been reported with injectable NAD+ products or commercial infusions