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[3] Degradation of lipoic acid is similar in humans, although it is not clear if the sulfur atoms become significantly oxidized

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Acylated ghrelin is an orexigenic hormone, and ghrelin level in children and young adults with PWS is higher than those of sibling control and early onset morbid obesity groups [13]

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None of the trials included in this review were of sufficient size or duration to assess key clinical outcomes related to weight management most notably, the risk of various weight-associated morbidities such as onset of type 2 diabetes and the risk of cardiovascular events

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Patients with a history of pancreatitis or gallbladder disease should inform their healthcare provider before starting the medication because these conditions may worsen with GLP-1 medications

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