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3.3 Iron metabolic reprogramming 3.3.1 Alterations in proteins governing iron uptake, storage, and export Ferroptosis is closely associated with dysregulated iron homeostasis, in which intracellular iron accumulation facilitates lipid peroxidation and cell death

For example, 4E-BP1, 4E-BP2, and Angel1-based peptides were developed and tested in different cancer cell lines (142144)

For patients, it is crucial to adhere to the physicians instructions accurately when it comes to medication administration via different routes, ensuring the correct dosage and timing are followed diligently

doi: 10.1016/j.mce.2013.01.016 58 WuJMinikesAMGaoMBianHLiYStockwellBRet al