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Inositol has a hand in the breakdown of fats and reducing blood cholesterol

Taking a proton pump inhibitor or other medications that reduce stomach acid for reflux or ulcers, as well as taking metformin for diabetes, can reduce absorption of B12 in food or supplements

AOD9604 and hGH significantly upregulated 3-AR expression in the WAT of ob/ob mice, correlating with the observed reductions in adipose tissue mass

The relationship between B12 and mental health is well established in medical literature, though it is primarily characterised by the psychiatric consequences of deficiency rather than excess