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Curcumin (200 mg/kg) significantly ameliorated brain injury and neurological deficits in rats subjected to middle cerebral artery occlusion by upregulating autophagy-related proteins p-Akt and p-mTOR, while downregulating autophagy-associated proteins LC3-II/LC3-I and inflammation-related proteins IL-1, TLR4, p-38 and p-p38

A routine B-12 shot can stabilize mood and serve as an effective measure to help prevent depressive relapses

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