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Hypothalamus, specifically the arcuate nucleus and the dorsal vagal complex in the brain stem, are the most relevant structures involved in this function.1 The role of the arcuate nucleus and the brain stem consists in an integration within signals coming from periphery and recognized in the gut hormones2 (Fig

Oral semaglutide eliminates the need for injections but requires strict dosing conditionsit must be taken on an empty stomach, with a small amount of water, and followed by a waiting period before food intake. For some patients, this routine may be more restrictive than a weekly injection

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