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They are naturally occurring in the body, and the therapeutic versions are carefully formulated to mimic or support those natural processes with minimal side effects

Pyrogen contamination is invisible Even if a home batch achieves sterility (no living organisms), it can still contain pyrogens endotoxin fragments from the cell walls of gram-negative bacteria that trigger fever, inflammation, and in severe cases, septic shock when injected

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That natural rhythm, combined with the regions of the brain where DSIP is found, is part of why it became associated with sleep regulation in the first place