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Dicembrini I, Nreu B, Montereggi C, Mannucci E, Monami M

If you have been on an adequate dose for 8-12 weeks with confirmed proper technique, storage, and supportive lifestyle factors, and you are still seeing no response whatsoever, you may be a non-responder to this particular medication

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While all causes and contributors of obesity are not within an individual's control, structured lifestyle modification programs can be effective and feasible to help achieve a 510 % weight reduction and maintain a healthy body weight for many people [[85], [86], [87]]