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Added to this, the increased exposure to a variety of toxins and pollutants from our modern lifestyles has created the need for even higher levels of antioxidants that can only be achieved through supplementation

Zinc and selenium were also used in the treatment of PCOS based on the fact that serum zinc and selenium levels in women with PCOS are significantly lower than in healthy controls (139141)

When insulin sensitivity improved through exercise or bariatric surgery, NNMT levels in adipose tissue fell suggesting NNMT activity tracks with metabolic state rather than being a passive marker