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It exists in a regulatory gray zone as a compound sold primarily 'for research use only.' In the United States, the FDA has taken an increasingly restrictive stance on this class of products
Because large publicly available datasets in American Latino ancestry are currently limited, replication was performed using the UK Biobank European ancestry GWAS as well as previously published studies identified through the GWAS Catalog 51,53,54
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Neither compound has published the kind of long-term hard-outcome data (cardiovascular events, mortality) that ultimately defines a metabolic drugs value, because both are too early in development for that
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