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(Folate deficiency disrupts normal DNA synthesis and methylation, which interferes with cell division and development, especially in rapidly dividing embryos.) Megaloblastic anemia, which can lead to symptoms like fatigue, weakness, and difficulty concentrating Elevated homocysteine, even when B12 levels are normal
Although both resolved and sensitized bladders have enhanced early Cox-2 responses in vivo, by 24 h post-infection, the bladder inflammatory response is only sustained in sensitized mice 7 and Cox-2 inhibition protects sensitized mice against severe recurrent cystitis 6,8
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