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Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, 44 (7), 1158-1166

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56 Decreased food intake and weight loss were observed with peripheral administration of GLP-1RAs, but inactivation of intestinal GLP-1 production did not interfere with food intake or weight control, suggesting that the GLP-1R-dependent signaling regulating appetite and body weight occurs in the CNS

Cyanocobalamin (Vitamin B12) Vitamin B12 plays a key role in fat metabolism, and a deficiency can be linked to increased fat accumulation and obesity