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2.8 SMR analysis SMR integrates cis-expression quantitative trait loci (cis-eQTL) and genome-wide association study (GWAS) summary data to infer causal relationships between tissue-specific gene expression and disease [25]

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Goldstein LB, Bushnell CD, Adams RJ, Appel LJ, Braun LT, Chaturvedi S, Creager MA, Culebras A, Eckel RH, Hart RG, Hinchey JA, Howard VJ, Jauch EC, Levine SR, Meschia JF, Moore WS, Nixon JV, Pearson TA

Understanding tirzepatide Tirzepatide works as a dual agonist at GIP (glucose-dependent insulinotropic peptide) and GLP-1 (glucagon-like peptide-1)