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Its receptor is not on the dividing crypt cells: it sits on subepithelial myofibroblasts and enteric neurons, which release IGF-1, IGF-2, KGF and nitric oxide to drive mucosal growth indirectly

Our specialists may prescribe this medication off-label from its intended use

JMs background metformin was continued As stressed in the ADA Standards of Care, metformin remains the recommended first-line pharmacologic therapy in patients with T2D and should be continued with the addition of other glucose-lowering therapies in those who can tolerate and do not have a contraindication to metformin therapy

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