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If the peptide is administered once in a way that creates a short signaling event, that protocol is functionally different from the same total amount divided across separate administrations

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The analysis was limited to a 6-month follow-up period, which may not capture the full magnitude or durability of treatment effects, as clinical trial data suggest that weight reduction typically continues beyond 6 months and often does not plateau until approximately 36 weeks or later, even at lower doses [24]