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the reduced dye then undergoes non-enzymic oxidation in air, so the addition of a relatively small amount of methylene blue will effectively deplete NADPH, and would be expected to stimulate any pathway that reduces NADP+ to NADPH

10.3390/molecules21030356 Summary Keywords alopecia, cacumen platycladi, hair follicles, dermal papilla cells, Akt, GSK3 Citation Fu H, Li W, Weng Z, Huang Z, Liu J, Mao Q and Ding B (2023) Water extract of cacumen platycladi promotes hair growth through the Akt/GSK3/-catenin signaling pathway