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The Brain Docs | Drs

Filipin staining confirmed decreased islet cholesterol content (Figure 1G), which correlated with increased exendin-4-induced cAMP responses (Supplementary Figure 1B), and exendin-4-induced insulin secretion (Figure 1H, I) in simvastatin-exposed islets

Cochrane Database Syst Rev 2013

The heterogeneity of T1DM might explain the negative results obtained, but previous trials have not addressed this issue