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A comparison of the effects of pegvisomant and octreotide on glucose, insulin, gastrin, cholecystokinin, and pancreatic polypeptide responses to oral glucose and a standard mixed meal

Populations Inclusion and Exclusion Criteria All studies except STEP 2 included patients with a BMI of 30.0 kg/ m 2 or greater, or 27.0 kg/m 2 or greater with the presence of at least 1 of the following weight-related comorbidities (treated or untreated): hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease (Table 6, Table 8, Table 9, and Table 10)

Color changes indicate chemical changes within stored solutions