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Synovial fluid and serum concentrations of inflammatory markers in rheumatoid arthritis, psoriatic arthritis and osteoarthitis: A systematic review

El estudio CANVAS, que incluy 4330 pacientes, doble ciego, con distribucin al azar, se realiz para evaluar a la semana 18 la eficacia y seguridad de la canagliflozina en pacientes con diabetes mellitus tipo 2 que ya reciban otros tratamientos

The pharmacokinetics suggest a half-life comparable to tirzepatide