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Pharmacoepidemiol Drug Saf (2001) 10(6):4836

Clinical studies have found these medications may: Improve insulin sensitivity Support healthier blood sugar regulation Improve certain cardiovascular risk factors Reduce inflammatory signaling Improve lipid profiles in some patients Researchers continue to investigate whether some of these benefits may occur independently of weight loss, although many questions remain about how these medications should be used outside their approved indications

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If a molecule with concerning HLA-DRB1 presentation is selected, then the immunogenic potential of those peptides from the biotherapeutic can be characterized for T cell proliferation potential in an allele-specific manner if desired