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Notably, among all classes of antidiabetic drugs, GLP-1RAs, a form of incretin (INtestinal secretion of INsulin) hormone-based therapy, offer additional advantages, such as inducing weight loss and preventing hypoglycemia symptoms

The proportion of the dose metabolised by this pathway increases in overdose and, potentially, in the presence of other pathological/physiological states [13, 18,19,20]

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Improper sealing and packaging also contribute to instability