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This damage is called oxidative stress

A combined potential biomarker model with Pyroglutamic acid and Kyn/Trp ratio for TTR V30M risk prognosis Peripheral plasma pyroglutamate (PGA) is a well-established biomarker of disrupted glutathione (GSH) homeostasis [65], whereas increased indoleamine 2,3-dioxygenase 1 (IDO1 ) activity, reflected by the kynurenine/tryptophan ratio, is a recognized marker of chronic inflammatory activation [61]

In fact, Vitamin C helps recycle oxidised glutathione back into its active form, allowing it to continue supporting cellular health and antioxidant defence

Antioxidants, such as vitamin C and vitamin E, have garnered increasing attention in the treatment of AP due to their ability to mitigate oxidative damage