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END STAGE RENAL PATIENTS ON HEMODIALYSIS Intravenous solution: Initial dose: 10 to 20 mg/kg as a slow 2 to 3 minute bolus injection into the venous return line after each dialysis session Consider therapy for pre-dialysis trough levels of plasma carnitine below normal (40 to 50 micromol/L)

Water/ethanol extracts often exhibit superior antioxidant activity compared to pure water or ethanol-only extracts, with two exceptions (169)

Accountability through regular monitoring and consultations