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At the molecular level, protein sensing by the Lcell involves the calcium sensing receptor (CaSR) and the peptide transporter 1 (PEPT1), with calcium being required for proteininduced GLP1 secretion (Diakogiannaki et al., 2013)

You may be more likely to experience histamine intolerance if you have an MTHFR gene variation.5 Histamine intolerance can be understood as your body struggling to manage too much histamine, a substance it naturally uses to function.6 Think of it like trying to fit too much into a 5-gallon bucketif you overfill it, things spill out and cause issues