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Among them, tryptophan metabolic bacteria such as Lactobacillus decreased, resulting in a decrease in the activity of diamine 2,3-dioxygenase (IDO) and tryptophan metabolites such as indo-3-lactate can inhibit Th 17 differentiation and promote Treg function via the aromatic hydrocarbon receptor (Zelante et al., 2013

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Specific primers used for PCR amplification were synthesized with the sequences as shown in Table 1 The relative expression levels of target genes were analyzed using the 2 Ct method

10.70976/j.1008-0805.SZGYGY-2025-0823 Lishizhen Med Mater Med Res