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The method of claim 1 , wherein the patient is a male patient, the sexual dysfunction is erectile dysfunction, the quantity of PDE-5 inhibitor administered and the quantity of PT-141 administered together is sufficient to initiate the desired pharmacological response in the patent and less than the quantity of either PDE-5 inhibitor administered as a monotherapy or PT-141 administered as a monotherapy to treat sexual dysfunction, and the quality of erection score is superior to that obtained from administration of a therapeutically effective amount of a single agent, administered as monotherapy, sufficient to initiate the desired pharmacological response in the patent

The exception to this rule is the single preparation of the sub-Q or IM dose that exceeds the volume safely injected at a single site