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At the same time, obesity and metabolic syndrome are themselves associated with worse vasomotor symptoms and a harder transition through menopause [2]

J Physiol Pharmacol (2016) 67:70915

More specifically, she explains, berberine increases beneficial microbes linked to improved metabolic health, like Akkermansia muciniphila , Bacteroides , Bifidobacterium , and Lactobacillus

Research to better understand and ultimately mitigate this heightened susceptibility is an important priority for new drug development in this area, and novel approaches to model the impact of endogenous hormone signaling will be critical to developing better treatments for more people