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Am J Physiol Regul Integr Comp Physiol (2000) 278(4):R105763
For David Cummings, director of the weight management program for VA Puget Sound Health Care System, side effects are less of a deciding factor
A negative feedback mechanism involving the hypothalamus, pituitary gland, and thyroid gland regulates thyroid hormones secretion as follows: The hypothalamus secretes TRH (thyrotropin-releasing hormone), which stimulates TSH (thyroid-stimulating hormone) release from the pituitary gland
In such cases, mitochondrial replacement therapy (MRT) has proven effective as a precautionary measure to prevent the inheritance of mtDNA mutations
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