Multiple dietary compounds have shown to be powerful agonists of GPR120, such as pinolenic acid, a poly-unsaturated fatty acid (C18:3 trans, cis, cis 5, 9, 12) found in pine nut oil (277), or the yeast derived phytosphingosine (278)
Having controlled glucose levels can help prevent severe complications from type 2 diabetes like kidney disease, retinal diseases, neuropathy (losing feeling in the hands and feet), and development of non-healing wounds in the feet, and experts are now looking into whether GLP-1s reduce the risk for those complications
This facilitates the development of all-in-one nanoplatforms capable of regulating the TME (e.g., enhancing O 2 supply and depleting GSH, enabling multi-enhanced therapies (e.g., PDT, SDT, CDT, RT), delivering immune adjuvants, and supporting imaging-guided, integrated immunocombinational cancer treatment (155, 156)
For example, a patient with beta- thalassemia major felt less tired after Vitamin B12 injections