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Investigating cerebral glucose uptake using 18FDG-positron emission tomography (PET) and visual evoked potentials between patients with interictal migraine without aura and healthy volunteers ( Figure 1 Lipid metabolism Lipids serve as a major form of energy storage and as precursors for molecules involved in inflammation and pain signaling

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Upon infusion, GLP-1 exerts potent vasodilatory effects on conduit artery and arterioles in healthy humans leading to increased blood flow for enhanced microvascular recruitment and muscular perfusion 46