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Glioblastoma stem cells and other cancer cells that are less sensitive to conventional therapies share markers that make them dependent on lipid metabolism and susceptible to ferroptosis [16]

NGF has poor bioavailability and cannot efficiently cross the BBB (Rogdakis et al., 2022), and it also has a short half-life (Jiang et al., 2024)

Participants on Zepbound also experienced substantial weight loss -- averaging 18% to 20% of their body weight (approximately 45 to 50 pounds) over the course of a year -- compared to 1.6% to 2.3% for those on placebo