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10.1007/s10863-011-9365-4 48 De GaudenziJ

62 One trial that included 40 dogs compared a combination product providing 500 mg glucosamine hydrochloride and 300 mg chondroitin sulfate per 10 kg body weight, along with 70 mg of an anti-inflammatory herbal combination, 4 mg non-hydrolyzed type II collagen, and 18 mg hyaluronic acid per 10 kg of body weight, to placebo daily for 60 days

Multiple regulatory mechanisms govern fibroblast activation and ECM deposition

All chromatograms were analyzed with Waters MassLynx v4.1 software (Waters TQD, United States)