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IGF-1 knock-out mice exhibited significant stunting in the development of vas deferens, seminal vesicles and prostate, along with developmental delay of Leydig cells, which were fewer than normal (67, 102)

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They have not been reviewed, evaluated, or approved by regulatory authorities for the diagnosis, treatment, cure, or prevention of any disease or medical condition

The researchers observed that treatment was associated with reduced adipocyte size and altered lipid accumulation compared to control groups