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This enhancement of detoxification pathways helps the body more efficiently eliminate harmful substances, including heavy metals, pesticides, and metabolic waste products, contributing significantly to overall milk thistle detox benefits

Obesity 23 , 290295 (2015)

These were L-NAME responsive/L-arginine responsive, L-NAME responsive/L-arginine non-responsive, L-NAME non-responsive/L-arginine responsive, opposite or parallel, NO-specific (L-NAME and L-arginine counteract each others response), or NO-non-specific (L-NAME and L-arginine do not counteract each others response) (Table 3)

NOS1 and NOS3 exhibit Ca-dependent activity and are expressed in striated muscle and endothelial cells