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However, data are lacking to back up their theory [48]

While the results can be impressive and last up to 18 months, the high price tag and the discomfort during the procedure are factors to consider

Stable, optimized thyroid hormone replacement (typically levothyroxine) must be established before considering weight loss medications, because untreated or under-treated hypothyroidism will sabotage any pharmacologic intervention

AMPA, KA, and NMDA receptors form tetrameric cation conductive channels that are activated by presynaptically released glutamate resulting in an influx of sodium and calcium ions leading to membrane depolarization 2