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Some patients report that unrefrigerated doses feel less effective, though they may not immediately recognize the cause

Paraesthesia (pins and needles) in the hands and feet often improves within two to four weeks, though complete resolution may take several months

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The accelerated healing in burns of treated mice includes the activity of the pentadecapeptide BPC 157 (Figure 1), given locally (as a cream) or systemically (ip), on the inflammatory cells, edema, reticulin, collagen, necrosis, blood vessel formation, number of preserved follicles, re-epithelization, tensile breaking strength, and water content in burned skin