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Hepatology 53 , 116126 (2011)

31,32 In diabetic peripheral neuropathy (DPN), macrophages infiltrate to initiate repairment on nerve injury, with more cytokine and chemokine released

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Persistent oxidative stress can result in irreversible cell damage and dysfunction, contributing to the clinical manifestations of DR, including neurodegeneration, vascular leakage, and vessel degeneration [9]