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Hurtado MD, Tama E, Fansa S, et al

Due to the increased release of PAI-1 and the thrombin activatable fibrinolysis inhibitor from liver and dysfunctional VAT, high-fat diet and obesity inhibit plasminogen activators (PAs) (e.g., t-PA and urokinase-type plasminogen activator) thus preventing clot dissolution [48, 49]

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