Experimental evidence is ongoing to explore and unravel all these possible beneficial mechanisms, while the combination of both drug categories (at least in patients with T2D) with or without other therapeutic strategies seems promising
Other Gastrointestinal Symptoms: In addition to nausea, vomiting, and diarrhoea, patients may also experience constipation , abdominal pain , or bloating during the first few weeks of treatment
References Akter N, Sobahan MA, Uraji M, Ye W, Hossain MA, Mori IC, Nakamura Y, Murata Y
However, pericytes provide pro-survival cues to angiogenic blood vessels, and their pharmacological targeting improves tumour response to anti-angiogenic therapy