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Male Sprague-Dawley rats were used for behavioral testing, with 24-month-old rats of mixed sex also included for aged rat models

However, inter-person variability in the expression and function of the organic cation transporters family (OCTs) can greatly affect the efficacy of metformin in individuals with neurologic disorders

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The biggest advantage of this technology is that it gives consistent results regardless of the heterogeneity of the N -Glycan forms, meaning that it can be used for any IgG isotypes with various N -glycosylation profiles