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CagriSema (closest analog) has Phase 3 data

Kim S, Kang JY, Nguyen QA, Lee JS (2024) Effects of Prebiotic Dietary Fibers on the Stimulation of the Mucin Secretion in Host Cells by In Vitro Gut Microbiome Consortia

Similar concerns apply to phosphodiesterase-5 inhibitors (medications like sildenafil) and L-arginine supplements that also influence nitric oxide signaling

doi: 10.1016/j.molmet.2019.09.010 Lee S, Lee DY