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10.7150/thno.51777 16 ChenS.LuK.HouY.YouZ.ShuC.WeiX.et al (2023)

No hot baths

Two individual ATDs assemble into ATD dimers (Figures 3A,C), while two ATD dimers assemble into a dimer-of-dimers configuration in the context of the KAR tetramer (Figures 3B,D)

The combination of GPX4 inhibitors with immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 axis increases the proportion of CD8 + T cells, enhances their cytotoxic activity and induces ferroptosis, thereby promoting chemotherapy resistance [42]