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Effectiveness and safety of the combination of sodium-glucose transport protein 2 inhibitors and glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of observational studies
It reduces blood pressure by 14 mmHg versus 6-7 mmHg for semaglutide and tirzepatide, and shows greater lipid improvements
Its safety has been confirmed by a recent study published in Lancet, whereby liraglutide had an efficacy comparable to that of glimepiride, but was associated with fewer cardiovascular events [140]
doi: 10.1161/CIRCULATIONAHA.113.005081 34 CastanedaAMDutra-RufatoAJuarezMJGrosembacherLGonzalez-TorresHMussoCG
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